For more detailed information on vaccinations, please see the CANIBD Vaccination Guide
TB skin test, blood work (baseline CBC, liver enzymes, lipids, CK, renal function, Hepatitis B serology)
Ensure all immunizations are current. Refer to CANIBD Vaccination Guidelines for further information.14
Infusion centre
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Induction: 300 mg IV wks 0, 4 and 8,
Evaluate patients after 12-week induction dosing and if there is adequate response transition to maintenance dosing.
If patients do not have adequate therapeutic response at week 12 after induction dosing, consider extended induction dosing by administering 300 mg IV at weeks 12, 16, and 20.
Maintenance:
200 mg SC (2 consecutive injections of 100 mg each) at wk 12 and every 4 wks thereafter.
Minimum 30-min infusion
Self-injection 5 min
Evaluate liver enzymes and bilirubin at baseline and every 1–4 mos during induction (including induction period, if applicable) and thereafter according to standard practice.
Annual cervical cancer screening – pap test
Annual skin exam – skin malignancies
Influenza vaccine recommended
Screening for osteoporosis with bone mineral density testing periodically after diagnosis