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SIDE EFFECTS

For more detailed information regarding side effects, please refer to the appropriate product monograph.

  • Infusion/injection site–related reactions – sometimes managed with pre-medications.
  • Increased risk of serious infection (sepsis and pneumonia), invasive fungal infections, and viral infections
  • Approximately 10% increased risk at wk 54 Reactivation of latent TB.
  • Can worsen pre-existing CHF
  • Lupus-like reaction (rare)
  • Hepatocellular damage, hepatitis, jaundice, autoimmune hepatitis; reactivation of HBV
  • Potential increased risk of malignancy (lymphoma, hepatosplenic T-cell lymphoma, melanoma, and NMSC); Increased frequency when used in combo with a thiopurine.
  • Numbness and tingling in legs, arms, etc.; change in vision, weakness in legs, dizziness